Cell age-related monovalent cations content and density changes in stored human erythrocytes
Conversion of erythrocyte membrane protein 4.1 b to 4.1 a occurs through a non-enzymatic
deamidation reaction in most mammalian erythrocytes, with an in vivo half-life of
approximately 41 days, making the 4.1 a/4.1 b ratio a useful index of red cell age [Inaba and
Maede, Biochim. Biophys. Acta 944 (1988) 256–264]. Normal human erythrocytes distribute
into subpopulations of increasing cell density and cell age when centrifuged in
polyarabinogalactan density gradients. We have observed that, when erythrocytes were …
deamidation reaction in most mammalian erythrocytes, with an in vivo half-life of
approximately 41 days, making the 4.1 a/4.1 b ratio a useful index of red cell age [Inaba and
Maede, Biochim. Biophys. Acta 944 (1988) 256–264]. Normal human erythrocytes distribute
into subpopulations of increasing cell density and cell age when centrifuged in
polyarabinogalactan density gradients. We have observed that, when erythrocytes were …
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